There is no clear-cut amount of weight that can be lost when taking XENICAL. Remember, in order for XENICAL to work optimally you must restrict your fat intake and increase exercise. If you are committed to your weight loss program there is essentially no limit as to how much weight you can loose. Nonetheless, weight loss should be gradual and always be done safely. While it is important that you decrease you fat intake it is equally as important that you eat healthy and insure you obtain all essential nutrients each and every day. Keep in mind that even a small amount of weight loss can reward you with a big gain in your health. A loss of 5 to 10% of your current weight can result in a significant reduction of risk for disease.